Showing posts with label compendium. Show all posts
Showing posts with label compendium. Show all posts

Sunday, July 13, 2008

Compendium Review Unit 4 Major Topic: Human Landscapes

I. Human Evolution
A. Origin of Life
B. Biological Evolution
C. Classification of Humans
D. Evolution of Hominids
E. Evolution of Humans
II. Global Ecology and Human Interferences
A. The Nature of Ecosystems
B. Energy Flow
C. Global Biogeochemical Cycles
III. Human Population, Planetary Resources, and Conservation
A. Human Population Growth
B. Human Use of Resources and Pollution
C. Biodiversity
D. Working Towards a Sustainable Society

I. Human Evolution
A. Origin of Life
chemical evolution
1. The primitive Earth
a. early Earth's atmosphere different than today's
b. atmosphere formed by gases escaping from volcanoes
c. atmosphere made up of H2O, N2, CO2, small amounts of H2, CO
d. water only existed as gas until Earth cooled, it rained forming oceans
2. Small organic molecules
a. rain washed gases into oceans
b. many sources of energy: volcanoes, meteorites, radioactive isotopes, lightning, ultraviolet radiation
c. energy + primitive gases react to produce small organic cmpds = nucleotides, amino acids (demonstrated in closed sys by Stanley Miller 1953)
3. Macromolecules new small organic molecules joined=macromolecules
a. RNA-first hypothesis - RNA as substrate and enzyme
b. protein-first hypothesis - amino acids joined to form microspheres
4. The protocell
a. microsphere + lipids = lipid-protein membrane
b. formation of protocell, probably a heterotroph & fermenter
5. The true cell
a. RNA-first hypothesis - genes of RNA specified protein synthesis (enzymes), enzymes used RNA to form DNA
b. protein-first hypothesis - proteins evolved enzymatic ability to synthesize DNA from nucleotides in ocean, DNA then specifies protein synthesis
Figure 22.1 illustrates chemical evolution. The following table from Professor Frolich's presentation lists some of the major events in Earth's history.B. Biological Evolution
1. Common descent
a. Charles Darwin - naturalist - theory of evolution
b. fossil evidence supports evolution
i. examples: traces - trails, footprints, burrows, worm casts, droppings; fossils - bone, impressions of plants, insects trapped in amber
ii. sediment -> strata - allows dating of fossils
iii. fossil record - most direct evidence that evolution has occurred, shows life has progressed from simple to complex (prokaryote->eukaryote->multicellular organism
c. biogeographical evidence - migration of ancestral species to isolated geographies allows evolution into different species
d. anatomical evidence - common descent hypothesis explains anatomical similarities among organisms of different species, despite functional differences
i. homologous structures - evidence of relatedness between organisms
ii. analogous structures
iii. vestigal structures - more evidence of common descent
iv. similarities in embryological development - eg paired pharyngeal pouches, postanal tail
Figure 22.6 from the text shows homologous structures.
e. biochemical evidence - same basic biochem molecules across almost all living organisms: DNA, ATP, enzymes, same triplet code in DNA, same 20 amino acids
2. Intelligent design
a. idea that diversity of life had to arise from the involvement of an "intelligent agent"
b. can not be tested in a scientific way
3. Natural selection - Darwin
a. described a mechanism for adaptation
b. variation - physical characteristics passed down to next generation
c. competition for limited resources - because of limited resources, not all individuals in a population survive
d. adaptation - those characteristics that give advantage to secure resources will be passed down to next generation. Over time, environment selects for the better-adapted traits
e. accounts for great diversity in life
Figure 22.9 from the text contrasts Jean-Baptiste Lamarck's process of acquired characteristics with Charles Darwin's process of natural selection.
C. Classification of humans
1. DNA data and human evolution
a. DNA/rRNA/protein sequencing data used compare and determine relatedness between species
2. Humans are primates adapted to arboreal life
a. mobile forelimbs and hindlimbs - easy grasping
b. binocular vision - accurate focusing
c. large, complex brain - sight, good hand-eye coordination
d. reduced reproductive rate - 1 birth at a time, extended junvenile dependency, learned behaviors, complex social interactions
3. Comparing human skeleton to the chimpanzee skeleton
a. human-spine exits center of skull-places skull in midline of body, chimpanzee-spine exits rear of skull
b. human spine s-shaped-trunk's center of gravity squarely over feet, chimp spine-slight curve
c. human pelvis & hip joint broader-no swaying when walking, chimp-narrow
d. human neck of femur longer-femur angles in at knees, chimp-femur angles out
e. human knee joint larger-supports body weight, chimp-smaller
f. human big toe not opposable, foot has arch-allows long walking and running, chimp opposable toe
D. Evolution of Hominids
1. The first hominids
a. first hominids and apes divereged from common ancestor - at time of divergence, genes and proteins of two lineages very similar
2. Hominid features
a. bipedal posture
b. shape of face- flatter face, more pronounced chin - human jaw shorter, smaller, l
i. flatter face, more pronounced chin b/c human jaw is shorter
ii. smaller, less specialized teetch
iii. larger brain
Figure 22.13 from the text shows the evolution of primates
3. Earliest fossil hominids
a. fossils found that date back to the time of ape and human lineage split
b. date between 7mya and 5mya
4. Evolution of autralopithecines
a. marks the earnest beginning of the hominid line of descent
b. gracile (slender) and robust (powerful) types
Figure 22.14 from the text shows a reconstruction of Lucy, the australopithecine, and footprints of A. afarensis.
5. Southern Africa
a. Australopithecus africanus - gracile type dated 2.8 mya
b. A. robustus - 2 to 1.5 mya
c. both walked upright, limb proportions apelike
6. Eastern Africa
a. 250 fossils of hominid A. afarensis - Lucy - found by Donald Johanson
b. walked bipedally
c. example of mosaic evolution (small apelike brain with bipedal ability)
E. Evolution of Humans
1. Early Homo
a. Homo habilis - 2.0-1.9mya, omnivores, used tools, cooperative hunting, hunters and gatherers shared food
b. Homo erectus (Asian form?)
i. larger brain, flatter face, nose projected - compared to H. habilis
ii. Homo ergaster (African form) - taller, robust, heavily musculed skeleton, small birth canal
iii. first to use fire, more advanced tools
Figure 22.15 from the text shows human evolution.
Figure 22.16 from the text show the skeleton of a 10 year old boy of the species Homo ergaster.2. Evolution of modern humans
a. multiregional continuity hypothesis
b. out-of-Africa hypothesis
3. Neandertals 200,000 years BP
a. massive brow ridge, nose, jaw, teeth protruded, low & sloping forehead, lower jaw lacked a chin
b. brain larger than Homo sapien's, maybe to control extra musculature
c. culturally advanced - built houses, used many tools & fire, buried dead
Figure 22.18 from the text illustrates how Neandertals may have looked and lived.
4. Cro-Magnons
a. oldest fossils to be designated Homo sapiens
b. entered Asia and Europe from Africa 100,000 yrs BP
c. DNA very different from Neandertal DNA - Neandertals probably cousins to Homo sapiens
d. made advanced tools (compound), experienced hunters may have caused extinction of larger animals
e. hunted cooperatively, women remained home with children
f. first to have language
g. culture included art
Figure 22.19 from the text illustrates the Cro-Magnons.
5. Human variation
a. humans geographically distributed
b. body shape and environment
i. cold temps - short limbs (Allen's rule), bulkier build (Bergmann's rule)
ii. warm temps - elongated limbs, slighter build
c. genetic evidence for a common ancestry
i. genetic differences in mDNA between different ethnic groups low - support out-of-Africa hypothesis

Definitions from Chapter 22 can be found here.

II. Global Ecology and Human Interferences
A. The Nature of Ecosystems
1. Ecosystems
a. tropical rain forest - at equator, large evergreen, broad-leaved tree
b. savanna - tropical grassland supports grazing animals
c. temperate grasslands (less rain than) temperate forests (trees lose leaves during winter)
d. desert - little water, no trees
e. taiga - very cold, norther coniferous forest
f. tundra - borders North Pole, very cold, long winters, permafrost
g. freshwater aquatic ecosystem - standing water (lakes, ponds), running water (rivers, streams), marshes where rivers meet sea
h. saltwater aquatic ecosystem - oceans, have coral reefs
Figure 23.1 from the text show the major terrestrial ecosystems.
Figure 23.2 from the text shows the major aquatic ecosystems.
2. Biotic components of an ecosystem
a. autotrophs (producers)-use inorganic nutrients plus energy source to produce organic nutrients, for self & for other members of community. Algae & plants
b. hetertroph (consumers) - need a source of organic nutrients
i. herbivores
ii. carnivores - primary, secondary, tertiary consumers
iii. omnivores
iv. detritus feeders - feed on detritus (decomposing particles of organic matter), break down dead organic matter & release inorganic substances that are taken up by plants. eg: earthworms, termites, ants, bacteria, fungi
Figure 23.3 shows some examples of bitotic components.
3. Energy flow and chemical cycling
a. most ecosystems require continual supply of energy from the sun
b. as organic nutrients are passed up the food chain, a smaller percentage of nutrients is available to higher-levels>
Figure 23.4 from the text illustrates energy flow and chemical cycling.
B. Energy Flow
1. Trophic levels
a. trees - producers - first trophic level
b. first series of animals eating trees - primary consumers - second trophic level
c. next group of animals - secondary consumers - third trophic level
2. Ecological pyramids
a. illustrates loss of 90% of energy between trophic levels.
b. therefore, few carnivores can be supported in food web
C. Global Biogeochemical Cycles
1. The water cycle
a. evaporation, precipitation, transpiration, gravity=water returns to sea, runoff, aquifers
b. human activities
i. withdraw water from aquifers
ii. clear vegetation from land, build roads, building - prevent percolation and increase runoff
iii. interfere with natural processes that purify water, add pollutants
Figure 23.9 from the test illustrates the hydrologic cycle.
2. The carbon cycle
a. CO2 in atmosphere is exchange pool for carbon cycle
b. plants take up CO2 - thru photosynthesis incorporate carbon into nutrients
c. carbon is returned to atmosphere as CO2 through respiration by organisms
d. CO2 in air combines with H2O to produce HCO3 bicarbonate ion. Source of carbon for algae
e. CO2 given off by aquatic organisms becomes bicarbonate ions
f. reservoirs for carbon=living & dead organisms, fossil fuels
g. human interference = burning of fossil fuels, destruction of forests puts more CO2 into atmosphere than is being used up
h. greenhouse gases allow solar radiation to pass thru but hinder the escape of infrared rays back into space
Figure 23.10 from the text illustrates the carbon cycle.
3. The nitrogen cycle
a. nitrogen fixation - N2->NH4 (form of nitrogen plants can use, by cyanobacteria and free-living bacteria in soil
b. nitrification - N2->NO3, needs high energy source, NH4->N02 by by soil bacteria, NO2->NO3
c. assimilation
d. denitrification
e. human interferences - N2 fertilizers, runoff causes overgrowth of algae, rooted aquatic plants.
f. acid deposition from burning fossil fuels: nitrogen oxides and sulfur dioxide enter atmosphere, combine w/water vapor to form acids
g. smog - nigrogen oxides and hydrocarbons combined
Figure 23.12 from the text illustrates the nitrogen cycle
4. The phosphorus cycle
a. phosphorus trapped in sediments moves to land after geological movement
b. weathering of rocks places phosphate ions into soil
c. plants use some (phospholipids, ATP, nucleotides)
d. animals eat producers, incorporate phosphate into teeth, bones, shells
e. death and decay make phosphate ions available to producers again
f. phosphate runoff into aquatic ecosystems, algae acquire some
g. humans boost supply by mining, runoff from fertilizer, animal waste, sewage planst results in cultural eutrophication of waterways
Figure 23.15 from the text illustrates the phosphorus cycle.
Figure 23.16 lists sources of surface water pollution.

Definitions for Chapter 23 can be found here.

III. Human Population, Planetary Resources, and Conservation
A. Human Population Growth
1. The MDCs - more developed countries
a. growth rate as a whole .1%, down from 1850-1950 when the population doubled
b. US growth rate .6%, immigrants, baby boom
c. total population expected to be at 1.2 billion by 2050
2. The LDCs - less-developed countries
a. growth rate at 1.6%
b. by 2050, population expected to jump from 5 to 8 billion
2. Comparing age structure
a. 3 age groups: prereproductive, reproductive, postreproductive
b. LDCs growth will continue, more young women in reproductive years
c. other than the US, MDCs have a stabilized age-structure diagram
Figure 24.1 from the text shows the human population growth.
Figure 24.2 shows the age-structure diagrams for MDCs and LDCs.
B. Human Use of Resources and Pollution
1. Land
a. beaches and human habitation - people like to live near the coastline - a place for fish spawning, habitats for terrestrial species, protection for coastal areas during storms
b. semiarid lakes and human habitation - humans allow animals to overgraze, they clear the land, use for fuel, fodder, water then runs off instead of being aborbed by remaining plants or replenishing wells, land becomes lifeless desert=desertification
c. tropical rain forest and human habitation - deforestation in tropical rain forests can cause desertification, loss of biodiversity
2. Water
a. increasing water supplies
i. dams - provide water, electricity. Rivers not making it to oceans, water loss to evaporation & seepage to rock beds, increase salinity, silt buildup
ii. aquifers - rain collected over hundreds of thousands of years ago, resource depletion - causes subsidence, sinkholes, saltwater intrusion
b. conservation of water - drought, salt-tolerant crops, drip irrigation, industries adopting conservation measures
3. Food food supply has increased since the 50s
a. modern/harmful farming methods - monoculture, fertilizers (production energy intensive, water pollution, kills good soil bacteria), irrigation, fuel consumption
b. positive practices - polyculture, contour farming, no-till
c. soil loss and degradation - erosion of topsoil (richest soil), sediment ends up in lakes and streams
d. green revolutions - varieties developed to yield more for in LDCs required same amount of fertizlier, water, pesticides, genetic engineering
e. domestic livestock - accounts for much pollution associated w/farming. 2/3 of cropland in US devoted to grow feed livestock. Much energy required to make food to feed livestock
Figure 24.10 from the text shows several methods of conservation.

4. Energy
a. nonrenewable sources - nuclear power, fossil fuels
b. burning of fossil fuels emites gases - rising temps threaten melting of glaciers, habitats threatened
c. renewable sources - hydropower, geothermal energy, wind power, solar
d. solar-hydrogen - using solar power to extract hyrdogen from water via electrolysis. Hydrogen can then be used as a clean-burning fuel
Figure 24.12 from the text shows 4 types of renewable energy sources.
5. Minerals
a. eg. fossil fuels, nonmetallic raw materials (sand, gravel, phosphate), metals (aluminum, copper, iron, lead, gold)
b. harmful to humans - heavy metals: lead, mercury, arsenic, cadmium, tin, chromium, zinc, and copper. Used to make batteries, electronics, pesticides, medicines, paints, inks, dyes
c. hazardous wastes - contributed by the consumption of minerals
d. 4 most common heavy metal contaminants - lead, arsenic, cadmium, chromium
e. 5 most common synthetic organic cmpds - trichloroethylene, toluene, benzene, polychlorinated biphenyls (PCBs), and cloroform.
f. synthetic organic chemicals - halogentaed hydrocarbons, used in production of plastics, pesticides, cosmetics, coatings, solvents...Chlorofluorocarbons (CFCs) - thinning of Earth's ozone. MDCs no longer use.
C. Biodiversity
1. Loss of biodiversity
a. habitat loss due to human interference
b. alien species
c. pollution - acid deposition, global warming, ozone depletion, synthetic organic chemicals
d. overexploitation
e. disease
2. Direct value of biodiversity
a. medicinal value - rosy periwinkle, penicillin, limulus in blood of horseshoe crab
b. agricultural value - natural predators, pollinators
c. consumptive use value - aquatic organisms, wild fruits, vegetables, trees
3. Indirect value of biodiversity
a. waste disposal - decomposers extremely useful to humans
b. provision of freshwater - after a storm forests soak up water and then release over a long period of time, preventing flooding
c. prevention of soil erosion - deforestation causes erosion, erosion causes silt buildup in dams and ecosystems
d. biogeochmeical cycles - keeps excess pollutants in environment under control
e. regulation of climate - trees provide shade, take up CO2, when cut, they release CO2, contributing to global warming
f. ecotourism
Figure 24.17 from the text provide examples of the direct benefits of wildlife.
D. Working Toward a Sustainable Society
1. Today's sustainable society
a. overpopulation of LDCs and overconsumption by MDCs both account for increasing poullution and extinction of wildlife
b. land used for human purposes
c. agriculture - big use of fossil fuels, use of pesticides, create pollution, use of freshwater
d. demand on freshwater
e. growing demand on energy sources
2. Characteristics of a sustainable society
a. use renewable energy
b. recycle materials
c. protect natural ecosystems
d. efficiency
e. rural sustainability - preserve ecosystems, cover crops, multiuse farming, composting, low flow or trickle irrigation, cultivars, precision farming, integrated pest management, plant variety of species, multipurpose trees, protect wetlands, buy local
f. urban sustainability - energy efficient transportation sys, solar/geothermal energy, green roofs, improve storm water mgmt, plant native grasses, greenbelts, revitalize old sections before developing new, control light and noise pollution, encourage recycling
3. Assessing economic well-being and quality of life
a. GNP - strictly economic
b. ISEW (index of sustainable economic welfare) - takes into account forms of value in addition to monetary value (environmental damage, natural resource depletion, distributional equite etc)
c. GPI (genuine progress indicator) - considers quality of life
d. use value, option value, existence value, aesthetic value, cultural value, scientific & educational value
Figure 24.18 from the text shows several unsustainable activities.

Definitions from Chapter 24 can be found here.

REFERENCES:
Mader, Syliva S. Human Biology. New York, NY: McGraw-Hill (2008).

Links provided throughout the summary take you to online sources.


IMPORTANT NOTE: Any time "text" or "the text" is referenced in the above summary, I am referring to the textbook Human Biology by Sylvia Mader (cited directly above).

Tuesday, July 1, 2008

Compendium Review Unit 3 Major Topic: Movement

Movement

I. Skeletal System
II. Muscular System

I. Skeletal System
A. Overview of Skeletal System
1. Functions of the skeleton
a. supports the body
b. protects soft body parts (skull, rib cage, vertebrae)
c. produces blood cells
d. stores minerals and fat
e. permits flexible body movement - along with muscles
2. Anatomy of a long bone
a. diaphysis with medullary cavity - compact bone, endosteum, yellowish bone marrow
b. epiphysis - articular cartilage, spongy bone containg red bone marrow
c. periosteum - covers long bone, is continuous with ligaments and tendons
d. bone
i. compact - osteon - lacunae - osteocyte. canaliculi connect lacunae, run thru matrix
ii. spongy - trabeculae (plates) separated by unequal spaces, filled with red bone marrow. osteocytes irregular placement in trabeculae
e. cartilage - flexible, chondrocytes in irregularly grouped lacunae, no nerves or vessels
i. hyaline cartilage - firm, somewhat flexible, ends of long bones, nose, ends of ribs, larynx, trachea
ii. fibrocartilage - strong, withstand tension & pressure, disk btwn vertebrae, knee
iii. elastic cartilage - more flexible than hyaline, ear flaps, epiglottis
f. fibrous connective tissue
i. ligaments
ii. tendons
Figure 11.1 from the text shows the anatomy of a long bone.











B. Bone Growth, Remodeling, and Repair osteoblasts, osteocytes, osteoclasts
1. Bone development and growth
a. intramembranous ossification - formation of bone developed between sheets of fibrous connective tissue. eg skull
b. endochondral ossification - bone growth occurs as bone replaces the cartilaginous models of the bones
i. cartilage model - chondrocytes lay down cartilage
ii. bone collar - matrix secreted from osteoblasts calcifies, covers diaphysis
iii. primary ossificaton center - osteoblasts in interior lay down spongy bone
iv. medullary cavity & secondary ossification sites - osteoclasts abosorb spongy bone of diaphysis, creates medullary cavity. secondary site form in epiphysis
v. epiphyseal (growth) plate - band of cartilage between primary & each secondary site.
vi. final size - determined when epiphyseal plates close
c. hormones affect bone growth - growth hormone, thyroid hormone,
2. Bone remodeling and its role in homeostasis
a. keeps bone strong, 18% of bone recycled each year
b. allows body to regulate amount of calcium in blood, if blood calcium is high, it can be deposited into bone, if low, calcium removed from bones
c. parathyroid hormone - accelerates bone recycling - increases blood calcium
d. calcitonin - hormone that acts opposite to PTH
e. allows bones to respond to stress -
f. walking, jogging, weight lifting - stimulates work of osteoblasts
3. Bone repair
a. hematoma
b. fibrocartilaginous callus
c. bony callus
d. remodeling
Figure 11.2 from the text illustrates endochondral ossification of a long bone. Additional images from the text can be found here.C. Bones of the Axial Skeleton
Figure 11.7 from the text shows the bones of the human skull.
1. The skull
a. cranium - protects brain, made of 8 bones in adults, some contain sinuses: frontal, parietal, occipital, temporal, sphenoid, ethmoid
b. facial bones
Figure 11.8 from the text shows the facial bones and the hyoid bone.
2. The hyoid bone
a. only bone that does not articulate with another bone
b. attached to temporal bones by muscles & ligaments, to larynx by membrane
c. anchors tongue, site for attachment of muscles associated w/swallowing
3. The vertebral column 33 vertebrae
Figure 11.9 from the text shows the vertebral column.
a. 4 curvatures provide more resilience & strength for upright position
b. protects spinal cord, site of attachment for muscles that move the vertebral column
c. types: cervical, thoracic, lumbar, sacral, coccyx
d. intervertebral disks - fibrocartilage = padding
4. The rib cage protective and flexible
a. composed of the thoracic vertebrae, the ribs & associated cartilages, & sternum
b. the ribs - 12 pairs, all connect to thoracic vertebrae, upper 7 connect w/sternum
c. the sternum - lies in midline of body, with ribs protect heart, lungs
i. composed of manubruim, body, xipoid process
Figure 11.10 from the text shows details of the thoracic verebrae and the rib cage.D. Bones of the Appendicular Skeleton
1. The pectoral girdle and the upper limb flexibility
Figure 11.11 from the text shows the bones of the pectoral girdle and the upper limb.
a. pectoral girdle: scapula, clavicle
b. upper limb: arm - humerus, forearm - radius, ulna, hand - carpals, metacarpals, phalanges
2. The pelvic girdle and lower limb strength
a. pelvic girdle: coxal bones
b. lower limbs: thigh - femur, leg - tibia, fibula, foot - tarsals, metatarsals, phalanges
Figure 11.12 shows the bones of the pelvic girdle and lower limb.E. Articulations
1. Joints
a. cartilaginous - connected by hyaline cartilage (costal cartilages that join ribs to sternum) or by fibrocartilage (intervertebral disks), tend to be movable
b. fibrous - many are immovable (sutures between cranial bones)
c. synovial - freely movable, contain bursa, menisci, synovial fluid
Figure 11.13 from the text shows synovial joints. Figure 11.14 illustrates synovial joint movements.









Definitions for Chapter 11 can be found here.

II. Muscular System
A. Overview of Muscular System
1. Types of muscles
a. smooth muscle fibers - spindle-shaped, uninucleated, form sheets, in walls of hollow internal organs, cause contraction (involuntary) of walls
b. cardiac muslce - forms heart wall, cells generally uninucleated, striated, tubular, branched (allowing interlocking of fibers at intercalated disks), gap junctions in plasma membrane, contraction rhythmical, involuntary
c. skeletal muscle fibers - tubular, multinucleated, striated, attached to skeleton, long - run length of muscle, voluntary
Figure 12.1 from the text shows the 3 types of muscle tissue.2. Functions of skeletal muscles
a. support the body - contraction opposes force of gravity, allows upright
b. make bones move
c. help maintain a constant body temp - heat from breakdown of ATP
d. contraction assists movement in cardiovascular and lymphatic vessels
e. help protect internal organs and stabilize joints
3. Skeletal muscles of the body
a. basic structure
i. fascicles - bundles of skeletal muscle fibers that make up a muscle
ii. connective tissue surrounds both fiber and fascicle
iii. fascia cover muscle and extend beyond muscle to become tendon
b. skeletal muscles work in pairs
i. prime mover - muscle doing most of the work, synergists - assist prime mover, antagonist - muscle that acts opposite to a prime mover
ii. origin & insertion, insertion - contracting muscle pulls on tendons at insertion
4. Names and actions of skeletal muscles
a. size - eg gluteus maximus
b. shape - eg deltoid, trapezius, latissimus, terres
c. location - eg external obliques, pectoralis, gluteus, brachii, sub
d. direction of muscle fibers - eg rectus abdominis, obicularis, trasverse, oblique
e. attachment - eg sternocleidomastoid, brachioradialis
f. number of attachments - eg biceps brachii, quadriceps femoris
g. action - eg extensor digitorum, adductor longus, flexor, masseter, levator
Figure 12.4 from the text shows the superficial skeletal muscles.B. Skeletal Muscle Fiber Contraction
Figure 12.5 shows skeletal muscle fiber structure and function.
1. Muscle fibers and how they slide
a. myofibrils and sarcomeres
i. muscle fibers->myofibrils->sarcomeres->myofilaments=actin & myosin
ii. actin - protein that makes up thin filaments (I band), attached to Z line
iii. myosin - protein that makes up thick filaments (H zone)
iv. action & myosin overlapping make up A band
b. myofilaments
i. thick filaments - several 100 molecules of myosin
ii. thin filaments - 2 intertwining strands of actin, tropomyosin, troponin
iii. sliding filaments - contraction of muscle fiber starts when calcium released from sarcoplasmic reticululm.
iv. sliding filament model - sarcomeres shorten by by actin filaments sliding past myosin filaments. actin fil. approach each other. myosin pull actin
v. ATP (broken down by myosin) supplies energy for muscle contraction
2. Control of muscle fiber contraction
a. nerve impulse reaches axon terminal, synaptic vesicles relase ACh into synaptic cleft
b. ACh binds to receptors in sarcolemma->generates impulses, spread down T tubules
c. sarcoplasmic reticulum releases Ca2+->leads to sarcomere contraction
d. Ca2+ combines with troponin, causes tropomyosin threads to shift, exposing myosin binding site on actin
e. ADP and P on myosin heads attach to actin filament
f. ADP and P are released and cross-briges bend sharply (power stroke)
g. ATP molecules bind to myosin heads, cross-bridges broken, heads detach from actin
h. ATP is hydrolyzed to ADP and P, process starts over, myosin reattaches further
along actin filament
i. cycle recurs until calcium ions are actively (requires ATP) returned to storage site in sarcoplasmic reticulum
Figure 12.6 from the text illustrates the neuromuscular junction and Figure 12.7 shows the function of calcium and myosin in muscle contraction.









C. Whole Muscle Contraction
1. Muscles have motor units
a. varying ratios of innervation - motor axons per muscle fiber (ie 1 motor neuron per 23 muscle fibers in the ocular muscles vs 1:1000 in the gastrocnemius)
b. muschel twitch - occurs when motor unit stimulation is infrequent
c. latent period, contraction period, relaxation period
d. tetanus achieved from summation of rapid series of stimuli
e. recruitment - when more and more muscle units in a muscle are activated upon increased intensity of nervous stimulation
f. muscle tone - when some motor units are always contracted, but not enough to cause movement
1. Energy for muscle contraction
a. fuel source for exercise
i. glycogen & fat stored in muscle
ii. blood glucose & plasma fatty acids
b. sources of ATP for muscle contraction, formation of ATP by:
i. creatine phosphate (CP) - anaerobic, CP pluls ADP = ATP & creatine
- CP formed only when muslce is resting, limited amt stored
- occurs in midst of sliding filaments
- used at beginning of submaximal exercise & during short-term, high-intensity exercise that lasts less than 5 seconds
ii. fermentation - anaerobic
- hormones provide signal to muscle cells to break down glycogen
- fast-acting, results in buildup of lactate
- oxygen debt required to complete metabolism of lactate
iii. cellular respiration - aerobic
- can use glucose from breakdown of glycogen, glucose taken up from blood, fatty acids
2. Fast-twitch and slow-twitch muscle fibers
Figure 12.11 shows fast- and slow-twitch muscle fibers.
a. fast-twitch fibers - (usually) anaerobic, designed for strength
i. motor units contain many fibers, explosions of energy
ii. light color b/c few mitochondria, little or no myoglobin, fewer blood vesssels
iii. vulnerable to accumulation of lactate = fatigue
b. slow-twitch fibers - (mostly) aerobic, more endurance
i. tire only when fuel supply is gone
ii. dark color b/c many mitochondria, contain myoglobin, dense capillary beds
iii. draw more blood & oxygen than fast-twitch
iv. lowe maximum tension, highly resistant to fatigue
v. steady, prolonged production of ATP when oxygen is available
3. Delayed onset of muscle soreness
a. thought to occur with any activity that causes muscles to contract while they are lengthening
b. prevention - warm up, cool down, start gradually with new activity
Figure 12.9 shows the fuel sources for muscle contraction during submaximal exercise (65-75% of effort) and figure 12.10 shows the 3 ways that muscles product ATP.










D. Muscular Disorders see definitions
1. Common muscular conditions
a. spasms, convulsions, cramps, facial tics, strain, sprain
b. tendinitis and bursitis
2. Muscular diseases
a. myalgia and fibromyalgia
b. muscular dystrophy
c. myasthenia gravis
d. amyotrophic lateral sclerosis
E. Homeostasis
1. Both systems produce movement
a. movement essential to maintaining homeostasis
b. skeletal & muscular systems work together to enable body movement
c. allow us to respond to changes in environment
d. other movements contribute to homeostasis - chewing food, contractions of peristalsis, beating of heart, movement aids in venous return
2. Both systems protecy body parts
3. Bones store and release calcium
4. Blood cells produced in bones
5. Muscles help maintain body temperature

Figure 12.12 shows how systems of the human body work together.

Definitions from Chapter 12 can be found here.

REFERENCES:
Mader, Syliva S. Human Biology. New York, NY: McGraw-Hill (2008).

Links provided throughout the summary take you to online sources.


IMPORTANT NOTE: Any time "text" or "the text" is referenced in the above summary, I am referring to the textbook Human Biology by Sylvia Mader (cited directly above).

Sunday, June 29, 2008

Compendium Review Unit 3 Major Topic: Nervous Function

Nervous Function

I. Nervous System
II. Senses

I. Nervous System
A. Overview of the Nervous System
1. Functions: receives sensory input, CNS performs integration, CNS generates motor output
2. Nervous tissue: neurons, neuroglia
3. Neuron types and structure

a. sensory neuron, interneuron, motor neuron
b. sensory receptors, effectors
c. cell body, dendrites, axon
4. Myelin sheath
a. formed by Schwann cells in PNS
b. formed by oligodendrocytes in CNS
c. gaps in sheath - nodes of Ranvier
d. gives white, glistening appearance to nerve fibers, good insulator
5. The nerve impulse
a. resting potential - axon not conducting impulse, inside more negative, more Na+ outside, more K+ inside, membrane permeable to K+
b. sodium-potassium pump
c. action potential
i. sodium gates open - Na+ flows in - depolarization: -65mV to +40mV
ii. potassium gates open - K+ flows out - repolarization: 40mV to -65mV
iii. sodium-potassium pump restores resting potential: Na+ out, K+ in
6. Propagation of an action potential
a. each action potential generates another along the length of an axon
b. unmyelinated axon - action potential at 1 locale stimulates adjacent part, 1m/sec
c. myelinated axon - saltatory conduction - 100m/sec
d. multiple sclerosis & leukodystrophies - demyelination - slows propagation
e. all-or-none event
f. intensity of message determined by how many nerve impulses are generated w/in a given time span
g. refractory period - sodium gates cannot open, ensures action potential cannot move backward
7. The synapse
a. axon terminal ends cell body or dendrite of another neuron
b. neurotransmitters transmit impulse across synaptic cleft
i. nerve impulses reach axon terminal
ii. Ca2+ enters terminal - stimulate synaptic vesicles to merge w/sending membrane
iii. neurtransmitter molecules released to synaptic cleft & diffuse to rcving membrane, bind with specific receptor proteins
c. neurotransmitters cause excitation (sodium gates open Na+ in) or inhibition (K+ in)
d. neurotransmitters removed from cleft after initiating response - prevents continuous stimulation/inhibition
e. neurotransmitter molecules
i. ACh, NE, dopamine, serotonin, glutamate, GABA
ii. drugs affecting nervous system: act by interfering w/ or potentiating the action of neurotransmitters
f. synaptic integration - summing of excitatory & inhibitory signals
Figure 13.4 from the text details the structure and fuction of the synapse.B. The Central Nervous System
1. The spinal cord
a. structure
i. gray matter - portions of sensory & motor neurons, interneurons, dorsal root - sensory fibers entering, ventral root - motor fibers exiting
ii. white matter - ascending tracts - info to brain - mostly dorsal, descending tracts - info from brain - mostly ventral
b. functions
i. means of communication btwn brain & peripheral nerves
ii. reflex actions
Figure 13.7 shows an overview of the spinal cord.2. The brain
a. the cerebrum (lateral ventricles)
i. cerebral hemispheres
ii. cerebral cortex - primary motor & sensory areas, association areas, processing centers, central white matter
b. the diencephalon (third ventricle)
i. hypothalamus -integration - maintains homeostasis-regulates hunger, sleep, thirst body temp, water balance. controls pituitary gland
ii. thalamus - rcvs sensory input, integration - visual, auditory, somatosensory, involved w/arousal of cerebrum
iii. pineal gland - secretes melatonin
c. the cerebellum (fourth ventricle)
i. rcvs sensory input - eyes, ears, joints, muslces
ii. rcvs motor output from cerebral cortex - where parts should be
iii. integration - sends motor impulses to skeletal muscles
iv. balance and posture
d. the brain stem - relay station for tracts btwn cerebrum & spinal cord or cerebellum, reflex centers for visual, auditory, tactile responses
i. pons - bundles of axons btwn cerebellum & rest of CNS, works w/medulla oblongata - regulate breathing, has reflex centers - head movement
ii. medulla oblongata - reflex centers - heartbeat, breathing, vasocontriction, vomiting, sneezing, coughing, hiccuping, swallowing
iii. reticular formation - major component of the reticular activating system
Figure 13.10 from the text shows the primary motor and somatosensory areas of the cerebral cortex. Other important images can be found here.C. The Limbic System and Higher Mental Functions
1. The limbic system
a. "evolutionary ancient group of linked structures deep w/in the cerebrum that is a functional group rather than an anatomical one."
b. blends primitive emotions and higher mental functions
c. amygdala - cause experiences to have emtotional overtones
d. hippocampus - learning and memory
2. Higher mental functions
a. memory and learning
i. short-term (prefrontal), long-term (semantic + episodic)
ii. skill memory - involves all motor areas of cerebrum below level of consciousness
iii. long-term memories stored in sensory association areas of cerebral cortex, hippocambus - bridge btwn association areas (storage) & prefrontal area (utilization)
3. Language and speech
i. dependent on semantic memory
ii. seeing & hearing words depends on sensory centers in occipital & temporal lobes
Figure 13.12 from the text illustrates the limbic system of the brain.D. The Peripheral Nervous System
1. Somatic system
a. serve skin, skeletal muscles, tendons
b. nerves - info from external sensory receptors to CNS, motor commands from CNS to skeletal muscles
c. reflexes & the reflex arc - path of nerve impulse when you touch a pin (sensory receptor hand - sensory fibers to dorsal-root ganglia - spinal cord - interneurons - motor neurons - effector )
2. Autonomic system
a. sympathetic and parasympathetic
i. preganglionic fibers arise from middle (thoracolumbar) partion of spinal cord
ii. function automatically and involuntary
iii. innervate all interanl organs
iv. utilize 2 neurons and 1 ganglion for each impulse
b. sympathetic division (NE primary neurotransmitter)
i. preganglionic fibers short, postganglionic fibers long
ii. fight or flight - accelerates heartbeat, dialates bronchi, ihibits digestive tract
c. parasympathetic division (ACh neurotransmitter)
i. few cranial nerves and fibers arising from sacral portion of spinal cord (craniosacral portion of autonomic sys)
ii. preganglionic fibers long, postganglionic fibers short
ii. promotes all internal responses associated with a relaxed state - pupil contraction, promotes digestion, retards heartbeat
Figure 13.14 from the text provides an overview of the PNS. Table 13.1 compares the motor pathways of the somatic and autonomic systems. Click here for images from the text of the somatic system and the autonomic system.E. Drug Abuse
1. Alcohol
2. Nicotine
3. Cocaine
4. Methamphetamine
5. Heroine
6. Marijuana


Definitions from Chapter 13 can be found here.

II. Senses
A. Sensory Receptors and Sensations
1. Types of sensory receptors
a. chemoreceptors
b. photoreceptors
c. mechanoreceptors
d. thermoreceptors
2. How sensation occurs
a. sensory receptors generate nerve impulse
b. if stimulus sufficient, nerve impulse travel along sensory fiber in PNS to CNS
c. nerve impulses reach spinal cord and conveyed to brain
d. if reach cerebral cortex,sensation & perception occur
e. sensory receptors carry out integration b4 initiating nerve impulses (eg sensory adaptation)
Figure 14.1 from the text shows a general overview of sensation and perception. Table 14.1 from the text lists several sensory receptors and related information.B. Proprioceptors and Cutaneous Receptors
1. Proprioceptors
a. mechanoreceptors
b. involved in reflex actions that maintain muscle tone
c. help us know position of limbs in space by detecting degree of muscle relaxation, stretch of tendons, movement of ligaments
2. Cutaneous receptors
a. located in dermal layer of skin, make skin sensitive to touch, pressure, pain, temp
b. touch - Meissner corpuscles, Krause end bulbs, Merkel disks, root hair plexus
b. pressure - Pacinian corpuscles, Ruffini endings
c. temperature - free nerve endings in epidermis
3. Pain receptors nociceptors
a. sensitive to chemicals released by damaged tissues
b. referred pain - eg pain from heart is felt in left shoulder and arm
Figure 14.3 from the text illustrates the various sensory receptors in the skin.C. Senses of Taste and Smell
1. Sense of taste
a. taste buds - on tongue, isolated on hard palate, pharynx, epiglottis
b. how the brain receives taste information - molecules bind to receptor proteins of microvilli on taste cells - nerve impulses generated - travel to brain - interpretation in gustatory cortex
2. Sense of smell
a. olfactory cells - 10 - 20 million high in nasal cavity
b. how the brain receives odor information
i. several hundred types receptor proteins - each olfactory cell has only 1 type
ii. like olfactory cells - nerves lead to same neuron in olfactory bulb
iii. odor molecules bind to specific receptors
iv. odor's signature in olfactory bulb determined by which neurons stimulated
v. neurons communicate info via olfactory tract to olfactory area of cerebral cortex
Figures 14.4 and 14.5 from the text show the taste and smell receptors.D. Sense of Vision
1. Anatomy and physiology of the eye
a. Table 14.2
b. function of the lens
i. cornea with lens and humors - focuses images on retina
ii. viewing near object - ciliary muscle contracts - tension released on suspensory ligaments - allows lens to round up
iii. viewing far object - ciliary muscle relaxed - suspensory ligaments taut - lens is flat
c. visual pathway to the brain
i. photoreceptors - absorption of light ->rod cells - rhodopsin splits into opsin & retinal - release of inhibitory molecules cease - signals go to other neruons in retina. ->cone cells - Blue, green, red pigments
ii. retina - rod & cone cells synapse with bipolar cells - synapse with ganglion cells whose axons become the optic nerve. many (150) rods active 1 ganglion. some cones activates 1 ganglion. integration occuring as signals pass to bipolar & ganglion
iii. blind spot
iv. from the retina to teh visual cortex - impulses from eyes along optic nerve to optic chiasma. fibers from rt 1/2 of each retina converge, continue in rt optic tract. fibers from left 1/2 of each retina converge, continue in left optic tract. fibers synapse with neurons in nuclei w/in the thalamus. nerve impulses to visual cortex
2. Abnormalities of the eye near & farsightedness, astigmatism
Figure 14.6 from the text shows the anatomy of the human eye. Additional images from the text can be found here.E. Sense of Hearing
1. Anatomy and physiology of the ear
a. outer ear - pinna, auditory canal
b. middle ear - tympanic membrane, oval & round window, ossicles (malleus, incus, stapes)
c. auditory tube
d. inner ear - semicircular canals & vestibules (equilibrium) & cochlea (hearing)
e. auditory pathway to the brain - tympanic memb. vibrates - to malleus, incus stapes (pressure multiplied x20). stapes strikes oval window - pressure to fluid in cochlea. movement of pressure waves from vetibular to tympanic canal across basilar membrane causes stereocilia of hair cells to bend. nerve impulses begin in cochlear nerve, travel to auditory cortext in temporal lobe for interpretation
Figures 14.13 and 14.14 illustrate the general anatomy of the ear and, more specifically, of the inner ear.F. Sense of Equilibrium
1. Rotational equilibrium pathway
a. mechanoreceptors in semicircular canals detect rotational equilibrium
b. displacement of cupula in ampulla causes stereocilia of hair cells to bend
c. pattern of impulses to brain changes
d. brain uses info to adjust motor output to right position in space
2. Gravitational equilibrium pathway
a. mechanoreceptors in utricle (back-forth movement) & saccule (up-down movement) detect movement of head in vert or horiz plane
b. movement causes displacement of otoliths, otolithic membrane sags, stereocilia of hair cells bend.
Click here for figure 14.15 from the text which shows the mechanoreceptors for equilibrium.

Definitions from Chapter 14 can be found here.

REFERENCES:
Mader, Syliva S. Human Biology. New York, NY: McGraw-Hill (2008).

Links provided throughout the summary take you to online sources.


IMPORTANT NOTE: Any time "text" or "the text" is referenced in the above summary, I am referring to the textbook Human Biology by Sylvia Mader (cited directly above).